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血管剪切波速與彈性模量數理關系研究
來源: | 作者: | 發布時間:2014-4-15 16:12:44

血管剪切波速與彈性模量數理關系研究
程娜,林江莉,陳科,尹光福
基金項目:教育部博士點基金(20100181110002);國家自然科學基金(30970781)
作者簡介:程娜(1989-),女,碩士生,主要研究方向:數值仿真,圖像處理,模式識別
通信聯系人:尹光福,男,教授,(1961-10),研究方向:生物醫學材料,生物功能材料.

(四川大學材料科學與工程學院生物醫學工程系,成都 610041)

摘要:剪切波傳播速度法是一種具有前景的無創測量血管彈性的方法,其中剪切波速與組織彈性的關系是一個重要的研究內容。目標:本文基于剪切波傳播速度法,研究血管中剪切波速與血管剪切彈性模量的數量關系。方法:運用有限元仿真剪切波傳播測量法獲得血管中傳播的剪切波速度,研究血管剪切彈性模量、血管壁厚和血管內徑的大小對其影響規律。結果:得出了血管中剪切波傳播速度與血管剪切彈性模量、血管壁厚和血管內徑的大小的數學解析10 式。結論:將數學關系式得到的速度和有限元仿真得到的速度進行比較,平均誤差在10%以內。
關鍵詞:血管;剪切波速度;彈性模量;有限元法
中圖分類號:R318.01

Research on the Mathematical Relation between Shear Wave Speed and Elastic Modulus in Vessel
CHEN Na, LIN Jiangli, CHEN Ke, YIN Guangfu
(Department of Biomedical Engineering of Materials Science and Engineering College, Sichuan University, Chengdu 610041)
Abstract: Shear wave velocity method is a promising method of non-invasive measurement of blood vessel elasticity, where the relationship between shear wave speed and elasticity is one of important research contents. Objectives: the relation between shear wave speed and elastic modulus in vessel is researched. Methods: based on the method, this paper utilizes FEM to obtain data of shear wave propogation, and study the influences of the shear elastic modulus,  vascular wall thickness and inside radius on shear wave velocity. Results: It is presented that the analytic formula between these influence factors and shear wave velocity. Conclusion: comparing the velocity obtained by the formula with by the FEM experiment,the result shows that the mean error range is less than 10%.
Key words: Vessel; Shear Wave Speed; Shear Elasticity Modulus ; Finite Element Method

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