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一種新型紅細胞光電探測模型的研究
來源: | 作者: | 發布時間:2014-4-15 17:54:36

 一種新型紅細胞光電探測模型的研究
郭永彩,張小明,高潮,周森
(重慶大學光電技術及系統教育部重點實驗室,重慶 400044)
摘要:本文介紹了一種新型的血紅細胞光散射探測模型。該模型基于扁橢球模型和反常衍射近似理論,應用數值模擬仿真技術,分別討論了血紅細胞形體變化、體積變化、取向角和相對折射率變化對光散射幅值分布的影響并建立了相應的圖譜分布,在文末對此模型進行了實驗驗證,結果表明在前向小角度內不同血紅細胞大小、不同相對折射率對光散射信息有著較大影響。這可以在龐雜的細胞中辨別不同的細胞類型,較好的應用于細胞分類研究領域。
關鍵詞:光散射;血紅細胞;反常衍射近似;扁橢球;仿真分析;實驗驗證
中圖分類號:TN247
A New Photoelectric Detection Model of Red Blood Cell
Guo Yongcai, Zhang Xiaoming, Gao Chao, Zhou Sen
(Key Laboratory Optoelectronic Technology and Systems of the Education Ministry of China,Chongqing University, ChongQing 400044)
Abstract: In this paper a new light scattering detection model of red blood cell was introduced. This model based on the oblate ellipsoid model and the anomalous diffraction approximation, The numerical analysis technique is applied to discuss the scattering amplitude affection of the blood cell separately, such as, in the variety of body, volume, relative refractive index and orientation angle, the dynamic relationship distribution is set up correspondingly, the model is proved by the experiment at the end of the paper. The simulation data indicate that the volume and relative refractive index of different red blood cell has the prominent effect on the scattering information in small range angle, which can help distinguish the different cell types in heterogeneous population of nucleated cells, so it can be well used in cell classification field.
Keywords: light scattering; red blood cell; anomalous diffraction approximation; oblate ellipsoid model; simulation analysis; experiment proving

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