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珍珠層作為骨修復材料的研究進展
來源: | 作者: | 發布時間:2014-4-15 18:29:05

珍珠層作為骨修復材料的研究進展
劉淵聲,黃千里,馮慶玲
(清華大學材料學院先進材料教育部重點實驗室,北京 100084)
摘要:尋找和研制理想的骨修復材料一直是生物材料研究的熱點之一。珍珠層作為生物骨替代材料,其優勢在于含有具有誘導成骨作用的有機成分、合適的降解性能以及與人骨組織接近的力學性能。本文綜述了珍珠層的結構、無機成分、有機成分、細胞相容性和生物降解性,這些研究結果表明,珍珠層具有很好的生物相容性。同時還分析了珍珠層作為骨修復材料存在的問題,展望了珍珠層作為骨修復材料應用的前景。
關鍵詞:珍珠層;骨修復材料;文石;生物相容性
中圖分類號:R318.08 文獻標志碼:A
Research progress in nacre as a bone repair material
Liu Yuansheng, Huang Qianli, Feng Qingling
(Key Laboratory of Advanced Materials of Ministry of Education of China, School of Materials
Science and Engineering, Tsinghua University, Beijing 100084, China)
Abstract: It is one of the primary hotspots in biomaterials field to find and develop ideal bone repair materials. The advantages of nacre as a bone repair material are that, it has bone growth factors, suitable degradation rate and similar mechanical properties as bone. This review summarizes the structure, inorganic composition, organic matrix, cytocompatibility and biodegradation of nacre. Current results show that nacre has good biocompatibility. Some problems and perspectives of nacre as a bone repair material are discussed as well.
Key words: nacre; bone repair material; aragonite; biocompatibility

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